Classic IL-6R signalling is dispensable for intestinal epithelial proliferation and repair

Inflammatory bowel disease is characterized by disturbed cytokine signalling in the mucosa. Inhibition of the proinflammatory interleukin (IL)-6 pathway is a promising new therapeutic strategy, but safety concerns arise as IL-6 signalling also contributes to epithelial repair of the intestinal mucos...

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Detalles Bibliográficos
Autores principales: Aden, K, Breuer, A, Rehman, A, Geese, H, Tran, F, Sommer, J, Waetzig, G H, Reinheimer, T M, Schreiber, S, Rose-John, S, Scheller, J, Rosenstiel, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141292/
https://www.ncbi.nlm.nih.gov/pubmed/27869785
http://dx.doi.org/10.1038/oncsis.2016.71

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141292/
https://www.ncbi.nlm.nih.gov/pubmed/27869785
http://dx.doi.org/10.1038/oncsis.2016.71

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