TruePrime is a novel method for whole-genome amplification from single cells based on TthPrimPol

Sequencing of a single-cell genome requires DNA amplification, a process prone to introducing bias and errors into the amplified genome. Here we introduce a novel multiple displacement amplification (MDA) method based on the unique DNA primase features of Thermus thermophilus (Tth) PrimPol. TthPrimP...

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Detalles Bibliográficos
Autores principales: Picher, Ángel J., Budeus, Bettina, Wafzig, Oliver, Krüger, Carola, García-Gómez, Sara, Martínez-Jiménez, María I., Díaz-Talavera, Alberto, Weber, Daniela, Blanco, Luis, Schneider, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141293/
https://www.ncbi.nlm.nih.gov/pubmed/27897270
http://dx.doi.org/10.1038/ncomms13296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141293/
https://www.ncbi.nlm.nih.gov/pubmed/27897270
http://dx.doi.org/10.1038/ncomms13296

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