Functional exploration of colorectal cancer genomes using Drosophila

The multigenic nature of human tumours presents a fundamental challenge for cancer drug discovery. Here we use Drosophila to generate 32 multigenic models of colon cancer using patient data from The Cancer Genome Atlas. These models recapitulate key features of human cancer, often as emergent proper...

Descripción completa

Detalles Bibliográficos
Autores principales: Bangi, Erdem, Murgia, Claudio, Teague, Alexander G.S., Sansom, Owen J., Cagan, Ross L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141297/
https://www.ncbi.nlm.nih.gov/pubmed/27897178
http://dx.doi.org/10.1038/ncomms13615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141297/
https://www.ncbi.nlm.nih.gov/pubmed/27897178
http://dx.doi.org/10.1038/ncomms13615

Ejemplares similares