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Improved anti-leukemia activities of adoptively transferred T cells expressing bispecific T-cell engager in mice
Despite the impressive clinical efficacy of T cells engineered to express chimeric antigen receptors (CAR-Ts), the current applications of CAR-T cell therapy are limited by major treatment-related toxicity. Thus, safer yet effective alternative approaches must be developed. In this study, we compare...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141353/ https://www.ncbi.nlm.nih.gov/pubmed/27258611 http://dx.doi.org/10.1038/bcj.2016.38 |