Improved anti-leukemia activities of adoptively transferred T cells expressing bispecific T-cell engager in mice

Despite the impressive clinical efficacy of T cells engineered to express chimeric antigen receptors (CAR-Ts), the current applications of CAR-T cell therapy are limited by major treatment-related toxicity. Thus, safer yet effective alternative approaches must be developed. In this study, we compare...

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Detalles Bibliográficos
Autores principales: Liu, X, Barrett, D M, Jiang, S, Fang, C, Kalos, M, Grupp, S A, June, C H, Zhao, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141353/
https://www.ncbi.nlm.nih.gov/pubmed/27258611
http://dx.doi.org/10.1038/bcj.2016.38

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