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Systemic TLR2 agonist exposure regulates hematopoietic stem cells via cell-autonomous and cell-non-autonomous mechanisms

Toll-like receptor 2 (TLR2) is a member of the TLR family of receptors that play a central role in innate immunity. In addition to regulating effector immune cells, where it recognizes a wide variety of pathogen-associated and nonpathogen-associated endogenous ligands, TLR2 is expressed in hematopoi...

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Detalles Bibliográficos
Autores principales: Herman, A C, Monlish, D A, Romine, M P, Bhatt, S T, Zippel, S, Schuettpelz, L G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141360/
https://www.ncbi.nlm.nih.gov/pubmed/27315114
http://dx.doi.org/10.1038/bcj.2016.45