Cargando…
Systemic TLR2 agonist exposure regulates hematopoietic stem cells via cell-autonomous and cell-non-autonomous mechanisms
Toll-like receptor 2 (TLR2) is a member of the TLR family of receptors that play a central role in innate immunity. In addition to regulating effector immune cells, where it recognizes a wide variety of pathogen-associated and nonpathogen-associated endogenous ligands, TLR2 is expressed in hematopoi...
Autores principales: | Herman, A C, Monlish, D A, Romine, M P, Bhatt, S T, Zippel, S, Schuettpelz, L G |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141360/ https://www.ncbi.nlm.nih.gov/pubmed/27315114 http://dx.doi.org/10.1038/bcj.2016.45 |
Ejemplares similares
-
Pten Cell Autonomously Modulates the Hematopoietic Stem Cell Response to Inflammatory Cytokines
por: Porter, Shaina N., et al.
Publicado: (2016) -
TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS
por: Monlish, Darlene A., et al.
Publicado: (2020) -
The Role of Toll-Like Receptors in Hematopoietic Malignancies
por: Monlish, Darlene A., et al.
Publicado: (2016) -
Prion infection modulates hematopoietic stem/progenitor cell fate through cell-autonomous and non-autonomous mechanisms
por: Sim, Hyun-Jaung, et al.
Publicado: (2023) -
The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex–mediated quiescence
por: Greenberg, Zev J., et al.
Publicado: (2023)