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A data-driven network model of primary myelofibrosis: transcriptional and post-transcriptional alterations in CD34+ cells

microRNAs (miRNAs) are relevant in the pathogenesis of primary myelofibrosis (PMF) but our understanding is limited to specific target genes and the overall systemic scenario islacking. By both knowledge-based and ab initio approaches for comparative analysis of CD34+ cells of PMF patients and healt...

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Detalles Bibliográficos
Autores principales: Calura, E, Pizzini, S, Bisognin, A, Coppe, A, Sales, G, Gaffo, E, Fanelli, T, Mannarelli, C, Zini, R, Norfo, R, Pennucci, V, Manfredini, R, Romualdi, C, Guglielmelli, P, Vannucchi, A M, Bortoluzzi, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141361/
https://www.ncbi.nlm.nih.gov/pubmed/27341078
http://dx.doi.org/10.1038/bcj.2016.47