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Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months

Up to 80% of the cost of vaccination programmes is due to the cold chain problem (that is, keeping vaccines cold). Inexpensive, biocompatible additives to slow down the degradation of virus particles would address the problem. Here we propose and characterize additives that, already at very low conc...

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Detalles Bibliográficos
Autores principales: Pelliccia, Maria, Andreozzi, Patrizia, Paulose, Jayson, D'Alicarnasso, Marco, Cagno, Valeria, Donalisio, Manuela, Civra, Andrea, Broeckel, Rebecca M., Haese, Nicole, Jacob Silva, Paulo, Carney, Randy P., Marjomäki, Varpu, Streblow, Daniel N., Lembo, David, Stellacci, Francesco, Vitelli, Vincenzo, Krol, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141364/
https://www.ncbi.nlm.nih.gov/pubmed/27901019
http://dx.doi.org/10.1038/ncomms13520