Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development

Notch1 signaling plays a critical role in maintaining and determining neural stem/progenitor cell (NSPC) fate, yet the transcriptional mechanism controlling Notch1 specific expression in NSPCs remains incomplete. Here, we show transcription factor Nkx6.1 interacts with a cis-element (CR2, an evoluti...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ying, Tzatzalos, Evangeline, Kwan, Kelvin Y., Grumet, Martin, Cai, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141430/
https://www.ncbi.nlm.nih.gov/pubmed/27924849
http://dx.doi.org/10.1038/srep38665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141430/
https://www.ncbi.nlm.nih.gov/pubmed/27924849
http://dx.doi.org/10.1038/srep38665

Ejemplares similares