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Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development
Notch1 signaling plays a critical role in maintaining and determining neural stem/progenitor cell (NSPC) fate, yet the transcriptional mechanism controlling Notch1 specific expression in NSPCs remains incomplete. Here, we show transcription factor Nkx6.1 interacts with a cis-element (CR2, an evoluti...
Autores principales: | Li, Ying, Tzatzalos, Evangeline, Kwan, Kelvin Y., Grumet, Martin, Cai, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141430/ https://www.ncbi.nlm.nih.gov/pubmed/27924849 http://dx.doi.org/10.1038/srep38665 |
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