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Impaired regenerative capacity and lower revertant fibre expansion in dystrophin-deficient mdx muscles on DBA/2 background

Duchenne muscular dystrophy, one of the most common lethal genetic disorders, is caused by mutations in the DMD gene and a lack of dystrophin protein. In most DMD patients and animal models, sporadic dystrophin-positive muscle fibres, called revertant fibres (RFs), are observed in otherwise dystroph...

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Detalles Bibliográficos
Autores principales: Rodrigues, Merryl, Echigoya, Yusuke, Maruyama, Rika, Lim, Kenji Rowel Q., Fukada, So-ichiro, Yokota, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141435/
https://www.ncbi.nlm.nih.gov/pubmed/27924830
http://dx.doi.org/10.1038/srep38371