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A central cavity within the holo-translocon suggests a mechanism for membrane protein insertion

The conserved SecYEG protein-conducting channel and the accessory proteins SecDF-YajC and YidC constitute the bacterial holo-translocon (HTL), capable of protein-secretion and membrane-protein insertion. By employing an integrative approach combining small-angle neutron scattering (SANS), low-resolu...

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Detalles Bibliográficos
Autores principales: Botte, Mathieu, Zaccai, Nathan R., Nijeholt, Jelger Lycklama à., Martin, Remy, Knoops, Kèvin, Papai, Gabor, Zou, Juan, Deniaud, Aurélien, Karuppasamy, Manikandan, Jiang, Qiyang, Roy, Abhishek Singha, Schulten, Klaus, Schultz, Patrick, Rappsilber, Juri, Zaccai, Giuseppe, Berger, Imre, Collinson, Ian, Schaffitzel, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141469/
https://www.ncbi.nlm.nih.gov/pubmed/27924919
http://dx.doi.org/10.1038/srep38399