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A central cavity within the holo-translocon suggests a mechanism for membrane protein insertion
The conserved SecYEG protein-conducting channel and the accessory proteins SecDF-YajC and YidC constitute the bacterial holo-translocon (HTL), capable of protein-secretion and membrane-protein insertion. By employing an integrative approach combining small-angle neutron scattering (SANS), low-resolu...
Autores principales: | Botte, Mathieu, Zaccai, Nathan R., Nijeholt, Jelger Lycklama à., Martin, Remy, Knoops, Kèvin, Papai, Gabor, Zou, Juan, Deniaud, Aurélien, Karuppasamy, Manikandan, Jiang, Qiyang, Roy, Abhishek Singha, Schulten, Klaus, Schultz, Patrick, Rappsilber, Juri, Zaccai, Giuseppe, Berger, Imre, Collinson, Ian, Schaffitzel, Christiane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141469/ https://www.ncbi.nlm.nih.gov/pubmed/27924919 http://dx.doi.org/10.1038/srep38399 |
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