Iron chelators target both proliferating and quiescent cancer cells

Poorly vascularized areas of solid tumors contain quiescent cell populations that are resistant to cell cycle-active cancer drugs. The compound VLX600 was recently identified to target quiescent tumor cells and to inhibit mitochondrial respiration. We here performed gene expression analysis in order...

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Detalles Bibliográficos
Autores principales: Fryknäs, Mårten, Zhang, Xiaonan, Bremberg, Ulf, Senkowski, Wojciech, Olofsson, Maria Hägg, Brandt, Peter, Persson, Ingmar, D’Arcy, Padraig, Gullbo, Joachim, Nygren, Peter, Schughart, Leoni Kunz, Linder, Stig, Larsson, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141479/
https://www.ncbi.nlm.nih.gov/pubmed/27924826
http://dx.doi.org/10.1038/srep38343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141479/
https://www.ncbi.nlm.nih.gov/pubmed/27924826
http://dx.doi.org/10.1038/srep38343

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