Effects of Liposomes Charge on Extending Sciatic Nerve Blockade of N-ethyl Bromide of Lidocaine in Rats

N-methyl bromide of lidocaine (QX-314) is a potential local anaesthetic with compromised penetration through cell membranes due to its obligated positive charge. Liposomes have been widely used for drug delivery with promising efficacy and safety. Therefore we investigated the local anaesthetic effe...

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Detalles Bibliográficos
Autores principales: Yin, Qinqin, Ke, Bowen, Chen, Xiaobing, Guan, Yikai, Feng, Ping, Chen, Guo, Kang, Yi, Zhang, Wensheng, Nie, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141481/
https://www.ncbi.nlm.nih.gov/pubmed/27924842
http://dx.doi.org/10.1038/srep38582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141481/
https://www.ncbi.nlm.nih.gov/pubmed/27924842
http://dx.doi.org/10.1038/srep38582

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