Structure and dynamics of a constitutively active neurotensin receptor

Many G protein-coupled receptors show constitutive activity, resulting in the production of a second messenger in the absence of an agonist; and naturally occurring constitutively active mutations in receptors have been implicated in diseases. To gain insight into mechanistic aspects of constitutive...

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Detalles Bibliográficos
Autores principales: Krumm, Brian E., Lee, Sangbae, Bhattacharya, Supriyo, Botos, Istvan, White, Courtney F., Du, Haijuan, Vaidehi, Nagarajan, Grisshammer, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141500/
https://www.ncbi.nlm.nih.gov/pubmed/27924846
http://dx.doi.org/10.1038/srep38564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141500/
https://www.ncbi.nlm.nih.gov/pubmed/27924846
http://dx.doi.org/10.1038/srep38564

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