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Structure and dynamics of a constitutively active neurotensin receptor
Many G protein-coupled receptors show constitutive activity, resulting in the production of a second messenger in the absence of an agonist; and naturally occurring constitutively active mutations in receptors have been implicated in diseases. To gain insight into mechanistic aspects of constitutive...
Autores principales: | Krumm, Brian E., Lee, Sangbae, Bhattacharya, Supriyo, Botos, Istvan, White, Courtney F., Du, Haijuan, Vaidehi, Nagarajan, Grisshammer, Reinhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141500/ https://www.ncbi.nlm.nih.gov/pubmed/27924846 http://dx.doi.org/10.1038/srep38564 |
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