Novel Concepts for Drug Hypersensitivity Based on the Use of Long-Time Scale Molecular Dynamic Simulation

The discovery that several drug hypersensitivity reactions (DHRs) are associated with specific human leukocyte antigen (HLA) alleles has attracted increasing research interest. However, the underlying mechanisms of these HLA-induced DHRs remain unclear, especially for drug-induced immediate activati...

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Detalles Bibliográficos
Autores principales: Murai, Takahiro, Kawashita, Norihito, Tian, Yu-Shi, Takagi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141551/
https://www.ncbi.nlm.nih.gov/pubmed/27999707
http://dx.doi.org/10.1155/2016/9520361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141551/
https://www.ncbi.nlm.nih.gov/pubmed/27999707
http://dx.doi.org/10.1155/2016/9520361

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