Global proteomic analysis of prenylated proteins in Plasmodium falciparum using an alkyne-modified isoprenoid analogue

Severe malaria due to Plasmodium falciparum infection remains a serious threat to health worldwide and new therapeutic targets are highly desirable. Small molecule inhibitors of prenyl transferases, enzymes that catalyze the post-translational isoprenyl modifications of proteins, exhibit potent anti...

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Detalles Bibliográficos
Autores principales: Suazo, Kiall F., Schaber, Chad, Palsuledesai, Charuta C., Odom John, Audrey R., Distefano, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141570/
https://www.ncbi.nlm.nih.gov/pubmed/27924931
http://dx.doi.org/10.1038/srep38615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141570/
https://www.ncbi.nlm.nih.gov/pubmed/27924931
http://dx.doi.org/10.1038/srep38615

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