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Global proteomic analysis of prenylated proteins in Plasmodium falciparum using an alkyne-modified isoprenoid analogue

Severe malaria due to Plasmodium falciparum infection remains a serious threat to health worldwide and new therapeutic targets are highly desirable. Small molecule inhibitors of prenyl transferases, enzymes that catalyze the post-translational isoprenyl modifications of proteins, exhibit potent anti...

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Detalles Bibliográficos
Autores principales:	Suazo, Kiall F., Schaber, Chad, Palsuledesai, Charuta C., Odom John, Audrey R., Distefano, Mark D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141570/ https://www.ncbi.nlm.nih.gov/pubmed/27924931 http://dx.doi.org/10.1038/srep38615

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