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Pleiotropic effects of acarbose on atherosclerosis development in rabbits are mediated via upregulating AMPK signals

Acarbose, an α-glucosidase inhibitor, is reported to reduce the incidence of silent myocardial infarction and slow the progression of intima-media thickening in patients with glucose intolerance. Here we investigate other impacts of acarbose on atherosclerosis development and the underlying mechanis...

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Detalles Bibliográficos
Autores principales: Chan, Kuei-Chuan, Yu, Meng-Hsun, Lin, Ming-Cheng, Huang, Chien-Ning, Chung, Dai-Jung, Lee, Yi-Ju, Wu, Cheng-Hsun, Wang, Chau-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141573/
https://www.ncbi.nlm.nih.gov/pubmed/27924924
http://dx.doi.org/10.1038/srep38642