Characterization of TET and IDH gene expression in chronic lymphocytic leukemia: comparison with normal B cells and prognostic significance

BACKGROUND: Chronic lymphocytic leukemia (CLL) is the most common hematological malignancy in western countries, characterized by a heterogeneous clinical course. Although genetic studies have identified chromosomal aberrations or specific mutations, epigenetic changes have been poorly characterized...

Descripción completa

Detalles Bibliográficos
Autores principales: Van Damme, Michaël, Crompot, Emerence, Meuleman, Nathalie, Maerevoet, Marie, Mineur, Philippe, Bron, Dominique, Lagneaux, Laurence, Stamatopoulos, Basile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141649/
https://www.ncbi.nlm.nih.gov/pubmed/27980696
http://dx.doi.org/10.1186/s13148-016-0298-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141649/
https://www.ncbi.nlm.nih.gov/pubmed/27980696
http://dx.doi.org/10.1186/s13148-016-0298-y

Ejemplares similares