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Characterization of TET and IDH gene expression in chronic lymphocytic leukemia: comparison with normal B cells and prognostic significance
BACKGROUND: Chronic lymphocytic leukemia (CLL) is the most common hematological malignancy in western countries, characterized by a heterogeneous clinical course. Although genetic studies have identified chromosomal aberrations or specific mutations, epigenetic changes have been poorly characterized...
Autores principales: | Van Damme, Michaël, Crompot, Emerence, Meuleman, Nathalie, Maerevoet, Marie, Mineur, Philippe, Bron, Dominique, Lagneaux, Laurence, Stamatopoulos, Basile |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141649/ https://www.ncbi.nlm.nih.gov/pubmed/27980696 http://dx.doi.org/10.1186/s13148-016-0298-y |
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