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Coordinated inhibition of C/EBP by Tribbles in multiple tissues is essential for Caenorhabditis elegans development

BACKGROUND: Tribbles proteins are conserved pseudokinases that function to control kinase signalling and transcription in diverse biological processes. Abnormal function in human Tribbles has been implicated in a number of diseases including leukaemia, metabolic syndromes and cardiovascular diseases...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Won, Thakur, Nishant, Piggott, Christopher A., Omi, Shizue, Polanowska, Jolanta, Jin, Yishi, Pujol, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141650/
https://www.ncbi.nlm.nih.gov/pubmed/27927209
http://dx.doi.org/10.1186/s12915-016-0320-z