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Systematic dissection of dysregulated transcription factor–miRNA feed-forward loops across tumor types

Transcription factor and microRNA (miRNA) can mutually regulate each other and jointly regulate their shared target genes to form feed-forward loops (FFLs). While there are many studies of dysregulated FFLs in a specific cancer, a systematic investigation of dysregulated FFLs across multiple tumor t...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Mitra, Ramkrishna, Lin, Chen-Ching, Wang, Quan, Cheng, Feixiong, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142013/
https://www.ncbi.nlm.nih.gov/pubmed/26655252
http://dx.doi.org/10.1093/bib/bbv107