Cargando…

The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism

Hypoxia-inducible factor (HIF) appears to function as a global master regulator of cellular and systemic responses to hypoxia. HIF pathway manipulation is of therapeutic interest; however, global systemic upregulation of HIF may have as yet unknown effects on multiple processes. We used a mouse mode...

Descripción completa

Detalles Bibliográficos
Autores principales: Slingo, Mary, Cole, Mark, Carr, Carolyn, Curtis, Mary K., Dodd, Michael, Giles, Lucia, Heather, Lisa C., Tyler, Damian, Clarke, Kieran, Robbins, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142182/
https://www.ncbi.nlm.nih.gov/pubmed/27422990
http://dx.doi.org/10.1152/ajpheart.00912.2015