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The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism
Hypoxia-inducible factor (HIF) appears to function as a global master regulator of cellular and systemic responses to hypoxia. HIF pathway manipulation is of therapeutic interest; however, global systemic upregulation of HIF may have as yet unknown effects on multiple processes. We used a mouse mode...
Autores principales: | Slingo, Mary, Cole, Mark, Carr, Carolyn, Curtis, Mary K., Dodd, Michael, Giles, Lucia, Heather, Lisa C., Tyler, Damian, Clarke, Kieran, Robbins, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142182/ https://www.ncbi.nlm.nih.gov/pubmed/27422990 http://dx.doi.org/10.1152/ajpheart.00912.2015 |
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