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Weight control interventions improve therapeutic efficacy of dacarbazine in melanoma by reversing obesity-induced drug resistance

BACKGROUND: Obesity-related cellular, metabolic, and molecular alterations have been shown to increase cancer risk and tumor progression and are associated with poorer therapeutic outcome in cancer patients. However, the impact of obesity and weight-control interventions on the therapeutic response...

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Detalles Bibliográficos
Autores principales: Malvi, Parmanand, Chaube, Balkrishna, Singh, Shivendra Vikram, Mohammad, Naoshad, Pandey, Vimal, Vijayakumar, Maleppillil Vavachan, Radhakrishnan, Revathy Meenatheril, Vanuopadath, Muralidharan, Nair, Sudarslal Sadasivan, Nair, Bipin Gopalakrishnan, Bhat, Manoj Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142287/
https://www.ncbi.nlm.nih.gov/pubmed/27980732
http://dx.doi.org/10.1186/s40170-016-0162-8