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A computational method for the investigation of multistable systems and its application to genetic switches

BACKGROUND: Genetic switches exhibit multistability, form the basis of epigenetic memory, and are found in natural decision making systems, such as cell fate determination in developmental pathways. Synthetic genetic switches can be used for recording the presence of different environmental signals,...

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Detalles Bibliográficos
Autores principales: Leon, Miriam, Woods, Mae L., Fedorec, Alex J. H., Barnes, Chris P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142341/
https://www.ncbi.nlm.nih.gov/pubmed/27927198
http://dx.doi.org/10.1186/s12918-016-0375-z