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A computational method for the investigation of multistable systems and its application to genetic switches
BACKGROUND: Genetic switches exhibit multistability, form the basis of epigenetic memory, and are found in natural decision making systems, such as cell fate determination in developmental pathways. Synthetic genetic switches can be used for recording the presence of different environmental signals,...
Autores principales: | Leon, Miriam, Woods, Mae L., Fedorec, Alex J. H., Barnes, Chris P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142341/ https://www.ncbi.nlm.nih.gov/pubmed/27927198 http://dx.doi.org/10.1186/s12918-016-0375-z |
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