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The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation

BACKGROUND: Human endogenous retroviruses (HERVs) constitute 8% of the human genome and contribute substantially to the transcriptome. HERVs have been shown to generate RNAs that modulate host gene expression. However, experimental evidence for an impact of these regulatory transcripts on the cellul...

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Detalles Bibliográficos
Autores principales: Broecker, Felix, Horton, Roger, Heinrich, Jochen, Franz, Alexandra, Schweiger, Michal-Ruth, Lehrach, Hans, Moelling, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142424/
https://www.ncbi.nlm.nih.gov/pubmed/27980690
http://dx.doi.org/10.1186/s13100-016-0081-9