Genetic engineering of chimeric antigen receptors using lamprey derived variable lymphocyte receptors

Chimeric antigen receptors (CARs) are used to redirect effector cell specificity to selected cell surface antigens. Using CARs, antitumor activity can be initiated in patients with no prior tumor specific immunity. Although CARs have shown promising clinical results, the technology remains limited b...

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Detalles Bibliográficos
Autores principales: Moot, Robert, Raikar, Sunil S, Fleischer, Lauren, Querrey, Melissa, Tylawsky, Daniel E, Nakahara, Hirotomo, Doering, Christopher B, Spencer, H Trent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142425/
https://www.ncbi.nlm.nih.gov/pubmed/27933313
http://dx.doi.org/10.1038/mto.2016.26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142425/
https://www.ncbi.nlm.nih.gov/pubmed/27933313
http://dx.doi.org/10.1038/mto.2016.26

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