Significant changes in endogenous retinal gene expression assessed 1 year after a single intraocular injection of AAV-CNTF or AAV-BDNF

Use of viral vectors to deliver therapeutic genes to the central nervous system holds promise for the treatment of neurodegenerative diseases and neurotrauma. Adeno-associated viral (AAV) vectors encoding brain-derived neurotrophic factor (BDNF) or ciliary derived neurotrophic factor (CNTF) promote...

Descripción completa

Detalles Bibliográficos
Autores principales: LeVaillant, Chrisna J, Sharma, Anil, Muhling, Jill, Wheeler, Lachlan PG, Cozens, Greg S, Hellström, Mats, Rodger, Jennifer, Harvey, Alan R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142514/
https://www.ncbi.nlm.nih.gov/pubmed/27933306
http://dx.doi.org/10.1038/mtm.2016.78

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142514/
https://www.ncbi.nlm.nih.gov/pubmed/27933306
http://dx.doi.org/10.1038/mtm.2016.78

Ejemplares similares