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Significant changes in endogenous retinal gene expression assessed 1 year after a single intraocular injection of AAV-CNTF or AAV-BDNF
Use of viral vectors to deliver therapeutic genes to the central nervous system holds promise for the treatment of neurodegenerative diseases and neurotrauma. Adeno-associated viral (AAV) vectors encoding brain-derived neurotrophic factor (BDNF) or ciliary derived neurotrophic factor (CNTF) promote...
Autores principales: | LeVaillant, Chrisna J, Sharma, Anil, Muhling, Jill, Wheeler, Lachlan PG, Cozens, Greg S, Hellström, Mats, Rodger, Jennifer, Harvey, Alan R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142514/ https://www.ncbi.nlm.nih.gov/pubmed/27933306 http://dx.doi.org/10.1038/mtm.2016.78 |
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