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Antiviral Innate Immune Response Interferes with the Formation of Replication-Associated Membrane Structures Induced by a Positive-Strand RNA Virus

Infection with nidoviruses like corona- and arteriviruses induces a reticulovesicular network of interconnected endoplasmic reticulum (ER)-derived double-membrane vesicles (DMVs) and other membrane structures. This network is thought to accommodate the viral replication machinery and protect it from...

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Detalles Bibliográficos
Autores principales: Oudshoorn, Diede, van der Hoeven, Barbara, Limpens, Ronald W. A. L., Beugeling, Corrine, Snijder, Eric J., Bárcena, Montserrat, Kikkert, Marjolein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142621/
https://www.ncbi.nlm.nih.gov/pubmed/27923923
http://dx.doi.org/10.1128/mBio.01991-16