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Marrow grafts from HLA-identical siblings for severe aplastic anemia: does limiting the number of transplanted marrow cells reduce the risk of chronic GVHD?

Twenty-one patients with severe aplastic anemia underwent marrow transplantation from HLA-identical siblings following a standard conditioning regimen with cyclophosphamide (50 mg/kg/day × 4 days) and horse antithymocyte globulin (30 mg/kg/day × 3 days). Post-grafting immunosuppression consisted of...

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Detalles Bibliográficos
Autores principales: Gallo, Susanna, Woolfrey, Ann E., Burroughs, Lauri M., Storer, Barry E., Flowers, Mary E.D., Hari, Parameswaran, Pulsipher, Michael A., Heimfeld, Shelly, Kiem, Hans-Peter, Sandmaier, Brenda M., Storb, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143192/
https://www.ncbi.nlm.nih.gov/pubmed/27479689
http://dx.doi.org/10.1038/bmt.2016.198