AB317. SPR-44 Pharmacological activation of individual KCNQ channel subtypes in detrusor smooth muscle represents a promising novel approach for overactive bladder treatment

OBJECTIVE: Our recent studies have demonstrated voltage-gated KCNQ channels (KCNQ1-KCNQ5) as key regulators of detrusor smooth muscle (DSM) function. Despite emerging developments, the physiological role of individual KCNQ channel subtypes remains less clear. Here, we utilized the novel compound ML-...

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Detalles Bibliográficos
Autores principales: Provence, Aaron, Angoli, Damiano, Petkov, Georgi V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2016
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143272/
http://dx.doi.org/10.21037/tau.2016.s317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143272/
http://dx.doi.org/10.21037/tau.2016.s317

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