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AMPKα Is Suppressed in Bladder Cancer through Macrophage-Mediated Mechanisms()()
Bladder cancer presents as either low- or high-grade disease, each with distinct mutational profiles; however, both display prominent mTORC1 activation. One major negative regulator of mTORC1 is AMPK, which is a critical metabolic regulator that suppresses cellular growth in response to metabolic st...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143351/ https://www.ncbi.nlm.nih.gov/pubmed/27916296 http://dx.doi.org/10.1016/j.tranon.2016.07.007 |