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AMPKα Is Suppressed in Bladder Cancer through Macrophage-Mediated Mechanisms()()

Bladder cancer presents as either low- or high-grade disease, each with distinct mutational profiles; however, both display prominent mTORC1 activation. One major negative regulator of mTORC1 is AMPK, which is a critical metabolic regulator that suppresses cellular growth in response to metabolic st...

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Detalles Bibliográficos
Autores principales:	Kopsiaftis, Stavros, Hegde, Poornima, Taylor, John A., Claffey, Kevin P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2016
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143351/ https://www.ncbi.nlm.nih.gov/pubmed/27916296 http://dx.doi.org/10.1016/j.tranon.2016.07.007

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