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High Expression of PHGDH Predicts Poor Prognosis in Non–Small Cell Lung Cancer()
Tumors have exceptionally high demands for energy and anabolism because of their rapid growth. The de novo serine synthesis pathway initiated by phosphoglycerate dehydrogenase (PHGDH) has been recognized as a hallmark of metabolic adaption in carcinogenesis. The oncogenic role and prognostic value o...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143353/ https://www.ncbi.nlm.nih.gov/pubmed/27916294 http://dx.doi.org/10.1016/j.tranon.2016.08.003 |