Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy

ABSTRACT: Impaired diastolic filling is a main contributor to heart failure with preserved ejection fraction (HFpEF), a syndrome with increasing prevalence and no treatment. Both collagen and the giant sarcomeric protein titin determine diastolic function. Since titin’s elastic properties can be adj...

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Detalles Bibliográficos
Autores principales: Hinze, Florian, Dieterich, Christoph, Radke, Michael H., Granzier, Henk, Gotthardt, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143357/
https://www.ncbi.nlm.nih.gov/pubmed/27889803
http://dx.doi.org/10.1007/s00109-016-1483-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143357/
https://www.ncbi.nlm.nih.gov/pubmed/27889803
http://dx.doi.org/10.1007/s00109-016-1483-3

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