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Proteolytic degradation and potential role of onconeural protein cdr2 in neurodegeneration

Cerebellar degeneration-related protein 2 (cdr2) is expressed in the central nervous system, and its ectopic expression in tumor cells of patients with gynecological malignancies elicits immune responses by cdr2-specific autoantibodies and T lymphocytes, leading to neurological symptoms. However, li...

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Detalles Bibliográficos
Autores principales: Hwang, J-Y, Lee, J, Oh, C-K, Kang, H W, Hwang, I-Y, Um, J W, Park, H C, Kim, S, Shin, J-H, Park, W-Y, Darnell, R B, Um, H-D, Chung, K C, Kim, K, Oh, Y J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143381/
https://www.ncbi.nlm.nih.gov/pubmed/27253404
http://dx.doi.org/10.1038/cddis.2016.151