BDNF pro-peptide regulates dendritic spines via caspase-3

The precursor of brain-derived neurotrophic factor (BDNF) (proBDNF) is enzymatically cleaved, by either intracellular (furin/PC1) or extracellular proteases (tPA/plasmin/MMP), to generate mature BDNF (mBDNF) and its pro-peptide (BDNF pro-peptide). Little is known about the function of BDNF pro-pepti...

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Detalles Bibliográficos
Autores principales: Guo, J, Ji, Y, Ding, Y, Jiang, W, Sun, Y, Lu, B, Nagappan, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143394/
https://www.ncbi.nlm.nih.gov/pubmed/27310873
http://dx.doi.org/10.1038/cddis.2016.166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143394/
https://www.ncbi.nlm.nih.gov/pubmed/27310873
http://dx.doi.org/10.1038/cddis.2016.166

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