Bax/Bak activation in the absence of Bid, Bim, Puma, and p53

How BH3-only proteins activate Bax/Bak, the two gateway proteins of the mitochondria-dependent apoptotic pathway, remains incompletely understood. Although all pro-apoptotic BH3-only proteins are known to bind/neutralize the anti-apoptotic Bcl-2 proteins, the three most potent ones, Bid (tBid), Bim,...

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Detalles Bibliográficos
Autores principales: Zhang, J, Huang, K, O'Neill, K L, Pang, X, Luo, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143395/
https://www.ncbi.nlm.nih.gov/pubmed/27310874
http://dx.doi.org/10.1038/cddis.2016.167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143395/
https://www.ncbi.nlm.nih.gov/pubmed/27310874
http://dx.doi.org/10.1038/cddis.2016.167

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