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α-Integrin expression and function modulates presentation of cell surface calreticulin

Calreticulin presentation on the cell surface is an important hallmark of immunogenic cell death (ICD), serving as the prophagocytic signal for macrophages. Cell adhesion is a physiologically relevant stimulus previously shown to increase calreticulin interaction with α-integrins via the juxtamembra...

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Detalles Bibliográficos
Autores principales: Liu, C-C, Leclair, P, Monajemi, M, Sly, L M, Reid, G S, Lim, C J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143402/
https://www.ncbi.nlm.nih.gov/pubmed/27310876
http://dx.doi.org/10.1038/cddis.2016.176