Engineered adenovirus fiber shaft fusion homotrimer of soluble TRAIL with enhanced stability and antitumor activity

Successful cancer therapies aim to induce selective apoptosis in neoplastic cells. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered an attractive anticancer agent due to its tumor cell-specific cytotoxicity. However, earlier studies with recombinant TRAIL revealed many s...

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Detalles Bibliográficos
Autores principales: Yan, J, Wang, L, Wang, Z, Wang, B, Zhu, R, Bi, J, Wu, J, Zhang, H, Wu, H, Yu, B, Kong, W, Yu, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143403/
https://www.ncbi.nlm.nih.gov/pubmed/27336718
http://dx.doi.org/10.1038/cddis.2016.177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143403/
https://www.ncbi.nlm.nih.gov/pubmed/27336718
http://dx.doi.org/10.1038/cddis.2016.177

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