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Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion

It is well accepted that junctophilin (JPHs) isoforms act as a physical bridge linking plasma membrane and endoplasmic reticulum (ER) for channel crosstalk in excitable cells. Our purpose is to investigate whether JPHs are involved in the proper communication between Ca(2+) influx and subsequent Ca(...

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Detalles Bibliográficos
Autores principales: Li, L, Pan, Z-F, Huang, X, Wu, B-W, Li, T, Kang, M-X, Ge, R-S, Hu, X-Y, Zhang, Y-H, Ge, L-J, Zhu, D-Y, Wu, Y-L, Lou, Y-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143404/
https://www.ncbi.nlm.nih.gov/pubmed/27336719
http://dx.doi.org/10.1038/cddis.2016.179