Cargando…
Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion
It is well accepted that junctophilin (JPHs) isoforms act as a physical bridge linking plasma membrane and endoplasmic reticulum (ER) for channel crosstalk in excitable cells. Our purpose is to investigate whether JPHs are involved in the proper communication between Ca(2+) influx and subsequent Ca(...
Autores principales: | Li, L, Pan, Z-F, Huang, X, Wu, B-W, Li, T, Kang, M-X, Ge, R-S, Hu, X-Y, Zhang, Y-H, Ge, L-J, Zhu, D-Y, Wu, Y-L, Lou, Y-J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143404/ https://www.ncbi.nlm.nih.gov/pubmed/27336719 http://dx.doi.org/10.1038/cddis.2016.179 |
Ejemplares similares
-
Postprandial blood glucose response to a standard test meal in insulin-requiring patients with diabetes treated with insulin lispro mix 50 or human insulin mix 50
por: Gao, Y, et al.
Publicado: (2008) -
Functional interaction of Junctophilin 2 with small‐ conductance Ca(2+)‐activated potassium channel subtype 2(SK2) in mouse cardiac myocytes
por: Fan, H. K., et al.
Publicado: (2017) -
Peroxisome proliferator-activated receptorβ/δ activation is essential for modulating p-Foxo1/Foxo1 status in functional insulin-positive cell differentiation
por: Li, L, et al.
Publicado: (2015) -
Munc18c mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose stimulated insulin secretion in human pancreatic beta-cells
por: Zhu, Dan, et al.
Publicado: (2015) -
Cortistatin hyperpolarizes pancreatic beta cell membrane and reduces glucose-stimulated insulin secretion
por: Rafacho, Alex, et al.
Publicado: (2015)