Cargando…

The role of local IL6/JAK2/STAT3 signaling in high glucose–induced podocyte hypertrophy

BACKGROUND: Interleukin-6 (IL6) is an important regulator of cellular hypertrophy through the gp130/Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) pathway. We tested the hypothesis that IL6 and its downstream gp130/JAK2/STAT3 pathway participated in high glucose (HG...

Descripción completa

Detalles Bibliográficos
Autores principales: Jo, Hyung Ah, Kim, Joo-Young, Yang, Seung Hee, Han, Seung Seok, Joo, Kwon Wook, Kim, Yon Su, Kim, Dong Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143438/
https://www.ncbi.nlm.nih.gov/pubmed/27957415
http://dx.doi.org/10.1016/j.krcp.2016.09.003